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As the anterior uveitis resolves, taper the steroid over a few weeks as appropriate based on the resolution of clinical signs and symptoms. Repeat steroids or steroids and NSAIDs can be added if necessary, but the initial dose should be lower than the initial prescription for NSAIDs when treating anterior uveitis, as the steroids, NSAIDs, or NSAIDs may worsen or block the efficacy of NSAIDs when used together. The dose adjustment and timing of the repeat dose of steroids are specific to the severity of the inflammatory process in the eye and the degree of inflammation. The dosage of NSAIDs should also be modified for the duration of their beneficial effects. As with NSAIDs, the dose of NSAIDs used in patients aged over 50 years is less than the dose used in younger individuals. It is important to administer NSAIDs correctly and at the correct time to prevent the potential for adverse effects on renal function. This is especially important for patients with diabetes mellitus who are at risk of developing hyperglycemia with the use of NSAIDs. The patient should be advised that the use of NSAIDs may reduce the effectiveness of topical corticosteroids because of interference with the action of glucocorticoid hormones on the immune response. The use of NSAIDs should also be avoided in patients with significant renal failure because this would increase the risk of serious renal complications, including acute tubular necrosis, which is a leading cause of renal failure in the United States. In patients with renal failure, it is important to closely monitor renal function before initiation of NSAIDs because the dosage and frequency of therapy should be carefully adjusted. Other treatment options for acute Uveitis Treatment of acute anterior uveitis with steroids may have limited therapeutic value in some situations as in other conditions associated with uveitis. For example, there is less evidence of efficacy in reducing the incidence of recurrent uveitis and the length of time after the original eruption that the lesions become necrotic or ulcerated. Further treatment of a patient with acute anterior uveitis with steroids may reduce the duration of treatment of the eye; however, the patient may need steroid-reliever medications for a short or long period after the initial steroid therapy. Similar articles: